FZUS61 KBUF 220205 GLFSL Forecast for the Saint Lawrence River including the Thousand Islands Region National Weather Service Buffalo NY 1005 PM EDT Tue Apr 21 2026 SLZ022-024-220900- Saint Lawrence River from Cape Vincent to Saint Regis 1005 PM EDT Tue Apr 21 2026 .OVERNIGHT...Southeast winds 5 to 10 knots. Mostly cloudy. .WEDNESDAY...Southeast winds less than 10 knots. Mostly cloudy through early afternoon, then becoming partly sunny. .WEDNESDAY NIGHT...Light and variable winds. Partly cloudy. .THURSDAY...Northwest winds 10 knots or less. Mostly sunny. .THURSDAY NIGHT...Northwest winds 10 knots or less becoming north. Partly cloudy. .FRIDAY...North winds 10 knots or less becoming east. Mainly clear. .SATURDAY...Northeast winds 5 to 10 knots becoming light and variable. Partly cloudy. .SUNDAY...Light and variable winds. Partly cloudy. $$